| 摘要: |
| 目的：探讨双源CT 4维血管造影（4D- CTA）及灌注成像（CTPI）在急性脑缺血性疾病中的应用价值。方法对30例临床拟诊为急性脑缺血性疾病的患者于发病2-24h内行头颅CT平扫和全脑CTPI检查，获得脑血流量、脑血容量、平均通过时间、达峰时间等参数图，同时获得4D- CTA图像；于发病的1-3d后行MRI检查，分析CT平扫、CTPI、4D- CTA、MRI表现。结果 CT平扫发现12例有16个缺血病灶，CTPI发现26例32个缺血病灶，MRI发现25例28个缺血病灶，4D- CTA显示有20例责任血管有不同程度的狭窄或闭塞。结论双源CT 4D- CTA联合灌注成像能为急性脑缺血患者提供全面、详细的影像学信息，对急性缺血性脑梗死的早期诊断和治疗有重要价值。 |
| 关键词: 脑缺血 体层摄影术 X线计算机 灌注成像 血管成像 |
| DOI： |
| 分类号:R743.31 |
| 基金项目: |
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| Application of dual-source 4D-CTA combined with CT perfusion imaging in diagnosis of acute cerebral ischemic diseases |
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CHENG Yougen, YANG Guangzhao, MAO Guoqun, et al( Department of Radiology, the Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou 310009, China)
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| Abstract: |
| Objective To investigate the application of dual- source four- dimensional CT angiography （4D- CTA） com-bined with CT perfusion imaging （CTPI） in diagnosis of acute cerebral ischemic diseases. Methods Thirty patients with clinical y suspected acute cerebral ischemic disease underwent head plain CT scan and whole brain CTPI examination 2~16h after onset, the images of CBF, CBV, MTT, TTP and 4D- CTA were obtained. Patients also underwent MRI examination in 1~3 d. The findings of plain CT scan, CTPI, 4D- CTA and MRI were analyzed. Results Plain CT scan found 16 ischemic lesions in 12 cases, CTPI found 32 ischemic lesions in 26 cases, MRI found 28 ischemic lesions in 25 cases, and 4D- CTA demonstrated various degree of stenosis or occlusion in supplying vessels in 20 cases. Conclusion Dual- source 4D- CTA combined with CT perfusion imaging provides comprehensive and detailed imaging information, so that has important value for early diagnosis and treatment in pa-tients with acute cerebral ischemia. |
| Key words: Brain ischemia Tomography X-ray computed Perfusion Angiography |
