| 摘要: |
| 目的 探讨ABCD2评分法结合房颤改良评分法（ABCD2F评分法）在短暂性脑缺血发作（TIA）患者早期脑梗死风险预测中的价值。方法 对260例TIA患者，按照ABCD2与ABCD2F评分法分别进行评分，观察两组患者2d和7d脑梗死发生率，用ROC曲线评价2种评分方法对于脑梗死的预测价值。根据2种评分法的危险分层（低、中、高危），进一步比较两组患者脑梗死发生率的差异，并对危险因素进行多元回归分析。结果TIA患者2d和7d脑梗死发生率分别为10.0%和16.1%。预测2d脑梗死风险，ABCD2及ABCD2F评分法的ROC曲线下面积分别为0.67和0.65；预测7d脑梗死风险，2种评分的ROC曲线下面积分别为0.63和0.62。对7d发生脑梗死的危险因素进行多元logistic回归分析发现，房颤是7d脑梗死的独立危险因素（P＜0.05）。按ABCD2评分法危险分层，低、中、高危各组的脑卒中发生率：2d为1.22%、12.8%、16.98%，7d为3.66%、18.40%、30.19%；按ABCD2F评分法危险分层，低、中、高危各组的脑卒中发生率：2d为0%、12.69%、16.98%，7d为1.37%、18.66%、30.19%；两种评分法各危险分层分组间脑梗死发生率的差异均有统计学意义（均P＜0.01）。结论ABCD2F评分具有早期脑梗死预测价值，结合房颤的危险分层更具精确性。 |
| 关键词: 短暂性脑缺血发作 脑梗死 ABCD2 评分 房颤 预测 |
| DOI： |
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| 基金项目: |
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| Modified ABCD2 score in early prediction of cerebral infarction after transient ischemic attack |
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WANG Liping,ZHU Renyang,DONG Fen
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Shaoxing People's Hospital
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| Abstract: |
| Objective To assess the application of modified ABCD2 score(ABCD2F), which was supplemented with a- trial fibrillation (AF), in early prediction of cerebral infarction after transient ischemia attack (TIA). Methods A total of 260 TIA patients were evaluated with ABCD2 and ABCD2F scores. The occurrences of cerebral infarction within 2 and 7 days were ob- served. Results Among 260 patients, cerebral infarction occurred in 26 cases(10.0%) within 2 d and in 42 cases(16.1%) within 7
d. The areas under curve of receiver operating characteristic curve (AUC-ROC)for ABCD2 and ABCD2F were 0.67 and 0.65 in predicting the risk of cerebral infarction within 2 d, and were 0.63 and 0.62 in predicting within 7 d, respectively. Logistic regres- sion analysis suggested that AF was an independent predictor of risk of cerebral infarction within 7 d (P＜0.05). The incidence of
cerebral infarction in patients with low, intermediate and high ABCD2 scores within 2 d and 7d was 1.22% 、12.8%、16.98% and
3.66% 、18.40% 、30.19% , respectively (P＜0.01). The incidence of cerebral infarction in patients of low, intermediate and high ABCD2F scored within 2 d and 7d was 0% 、12.69%、16.98% and 1.37%、18.66%、30.19%，respectively (P＜0.01). Conclusion The ABCD2F score is more accurate than ABCD score in predicting early cerebral infarction in patients with transient ischemic at- tack. |
| Key words: Transient Ischemia attack(TIA) Cerebral Infarction ABCD2 Score Atrial Fibrillation(AF) Prognosis |
