| 摘要: |
| 目的探讨 3.0T 磁共振扩张量成像（DTI）在椎间盘突出中的应用。 方法 回顾 30 例腰椎间盘突出患者和 30 例 健康志愿者的磁共振平扫和 DTI 资料，测量两组 L3~S1 双侧神经根的表现扩散系数（ADC）、部分各向异性（FA）及纤维来示踪成像
（DTT）显示神经根走行情况，比较椎间盘突出患者受压神经根与非受压神经根、健康志愿者正常神经根 ADC 值、FA 值的差异。 结 果 健康志愿者正常神经根及腰椎间盘突出患者受压神经根与非受压神经根的 ADC 值、FA 值分别为（2.248±0.048）×10-3mm2/s、
（2.751±0.052）×10-3mm2/s 、（2.255±0.044）×10-3mm2/s 和 0.207±0.015、0.178±0.019、0.209±0.011。受压神经根的 ADC 值
明显高于非受压神经根和正常神经根，差异均有统计学意义（均 P＜0.01），而受压神经根的平均 FA 值明显低于非受压神经根和正常 神经根，差异均有统计学意义（均 P＜0.01）。DTT 清晰显示神经根正常走行及受压改变。 结论 3.0T 磁共振 DTI 技术 ADC 值、FA 值在腰椎间盘突出致神经根受压时有明显改变，DTT 技术能够直观多方位显示神经根走行，对临床诊断和术前定位有指导意义。 |
| 关键词: 磁共振成像 扩散张量成像 腰骶丛 椎间盘突出 |
| DOI： |
| 分类号: |
| 基金项目:湖州市科技局项目 |
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| Application of MR diffusion tensor imaging in diagnosis of lumbar disc herniation |
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Qian Haifeng, Wu Xiao, Xu Wanli, Xuan Haobo, Hu Mingfan
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Huzhou Central Hospital
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| Abstract: |
| Objective To assess the application of MRI diffusion tensor imaging (DTI) in diagnosis of lumbar disc herniation. Methods MR examination and DTI were performed in 30 patients of lumbar disc herniation and 30 healthy volunteers. The mean fractional anisotropy (FA) and apparent diffusion coefficient (ADC) values of L3, L4, L5 and S1 nerves in both sides were calculated by DTI, and these nerves were observed by diffusion tensor tractography (DTT). Results The ADC and FA value of the normal spinal nerve roots in healthy volunteers and those of the compressed and uncompressed spinal nerve roots in patients were (2.248±0.048) ×10-3 mm2/s, (2.751±0.052) ×10-3 mm2/s, (2.255±0.044) ×10-3 mm2/s and 0.207±0.015, 0.178±0.019,
0.209±0.011. The ADC values of the compressed spinal nerve roots were significantly lower, and the FA values were significantly higher than those of the uncompressed and normal spinal nerve roots(P＜0.01). Conclusion The ADC and FA values at MR DTI of the compressed spinal nerve roots are significantly changed in patients with lumbar disc herniation. The lumbar plexus nerve roots can be visualized clearly by using DTT, and it may helpful in preoperative localization of the lesions. |
| Key words: Magnetic resonance imaging Diffusion tensor imaging Lumbar plexus Disc herniation |
