| 摘要: |
| 目的 探讨早产儿视网膜病变（ROP）与母体因素的相关性。 方法 将 2010 年 1 月至 2011 年 12 月在 NICU 治疗 的 493 例早产儿纳入研究，其中无 ROP452 例，有 ROP41 例。记录早产儿母亲宫内感染、胎盘异常、妊娠期相关疾病等 16 项指标，分 析 ROP 与母体因素的相关性。 结果 早产儿 ROP 发生率为 8.3%。ROP 与早产儿出生体重呈正相关（r=0.135，P＜0.05）；母亲宫内 感染、胎盘异常的早产儿 ROP 发生率较高（均 P＜0.05）。 结论 ROP 与早产儿出生体重、母亲胎盘异常和宫内感染相关，应尽早对 以上因素进行干预。 |
| 关键词: 早产儿视网膜病变 母体因素 相关性 |
| DOI： |
| 分类号: |
| 基金项目:浙江省自然科学基金资助项目;温州市科学技术局公益性科技计划项目 |
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| Maternal and neonatal factorsassociated with retinopathy of prematurity |
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LIU Dan, CHEN Ru, CHEN Jieling, YANG Boyu, ZHEN Huilian
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the Second Affliated Hospital and Yuying Children’s Hospital of Wenzhou Medical University
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| Abstract: |
| Objective To analyze the maternal and neonatal factors associated with retinopathy of prematurity (ROP). Methods In this prospective cohort study, all preterm infants were screened for ROP at the Neonatal Intensive Care Unit (NICU) of the second Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University between January 2010 and December 2011. The rate of ROP, and the maternal and neonatal factorsassociated with the diseasewere analyzed. Results A total of 493 newborns were screened for ROP, of which 41 cases (8.3% ) were identified. Low birth weight (r=0.135, P ＜0.05), placental abnormality (P＜0.05) and intrauterine infection (P＜0.05) were associated with the ROP. Conclusion Aimed at the risk factors, intervention should be conducted to prevent retinopathy of prematurity. |
| Key words: Retinopathy of prematurity Maternal factors Correlation |
