| 摘要: |
| 目的探讨肺部CT不同性质肺结节在早期肺癌诊断的临床意义。方法收集不同CT性质肺结节的早期肺癌患者52例，按肺结节CT性质分单纯磨玻璃结节组（9例）、混合磨玻璃结节组（19例）、实性结节组（24例），比较肺结节CT性质、大小变化、实体成分比例与病理学类型的关系。结果3种不同CT性质肺结节在4种早期肺癌病理类型中的分布有统计学差异（字2=17.784，P＜0.05）。其中，单纯磨玻璃结节组中非典型腺瘤样增生比例较实性结节组高，腺癌比例较实性结节组低，差异均有统计学意义（字2=5.424、6.017，均P＜0.05）。4种病理学类型的肺结节直径差值不同，但差异无统计学意义（P＞0.05）。肺结节实体成分比例与病理学类型正相关（rs=0.279，均P＜0.05）。结论肺结节CT性质、实体成分比例与病理学类型存在相关性。随着肿瘤大小和实体成分增加，肿瘤的侵袭性有增强趋势。术前准确判定肺结节变化并与微创手术结合是患者获益的诊治方法。 |
| 关键词: 肺结节 早期肺癌 诊治 |
| DOI： |
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| 基金项目:浙江省重大科技专项重大社会发展项目 |
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| Correlation of different pulmonary nodules on CT scan with pathological diagnosis of early lung cancer |
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FU Xiaoqing, YANG Yong, DONG Liwen, WANG Jun, XIE Baisheng
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Hangzhou hospital of TCM
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| Abstract: |
| Objective To investigate the correlation of different pulmonary nodules on CT scan with pathological diagnosis of early lung cancer. Methods Fifty two early lung cancer patients with different pulmonary nodules on CT scan, including 9 cases of pure ground-glass opacity(pGGO), 19 cases of mixed ground-glass opacity(mGGO) and 24 cases of solid nodules, were enrolled in the study. The correlation of pathological diagnosis with nodule size, CT features and parenchyma/tumor ratio(C/T) were analyzed. Results The ratio of atypical adenomatous hyperplasia(AAH) in pGGO group was significantly higher than that in solid nodules group, the ratio of adenocarcinoma in solid nodules group was significantly higher than that in pGGO group(P＜0.05). The size of nodules was not correlated with pathological types(P ＞0.05), However, there was significant correlation of C/T with pathological types(rs=0.250, P＜0.05). Conclusion The CT features and C/T ratio of lung nodule are correlated with their pathological types. |
| Key words: Pulmonary nodule Early lung cancer Diagnosis and treatment |
