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阻塞性睡眠呼吸暂停低通气综合征及单纯性鼾症儿童的睡眠结构研究
何梦藻, 金剑, 滕懿群
嘉兴市第二医院儿科
摘要:
目的 通过比较阻塞性睡眠呼吸暂停低通气综合征(OSAHS)和单纯性鼾症(PS)患儿睡眠结构间的差异,探讨 OSAHS 和 PS 对儿童睡眠结构的影响。 方法 对 96 例打鼾儿童进行多导睡眠监测,区分为 OSAHS 组 42 例和 PS 组 54 例,比较两 组患儿的睡眠结构异同,并与同年龄组正常儿童睡眠结构正常值进行比较。 结果 两组患儿的总睡眠时间、睡眠潜伏期、睡眠效率、 睡眠各期(N1 期、N2 期、N3 期、REM 期)百分比、微觉醒指数均无统计学差异(均 P >0.05),而 BMI、呼吸暂停低通气指数(AHI)、最低 动脉血氧饱和度(LSaO2)组间比较均有统计学差异(均 P<0.05)。与正常组儿童睡眠结构各项指标相比,两组患儿 N1、N2 期睡眠比例 增加,N3 期、REM 期睡眠比例减少(均 P<0.01)。 结论 OSAHS 和 PS 均可导致儿童睡眠结构紊乱,但 OSHAS 与 PS 患儿的睡眠 结构差异不明显。
关键词:  阻塞性睡眠呼吸暂停低通气综合征 单纯性鼾症 儿童 睡眠结构 多导睡眠监测
DOI:
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基金项目:浙江省医药卫生平台骨干人才计划B类项目
Sleep architecture in children with obstructive sleep apnea/hypopnea syndrome and primary snoring
HE Mengzao, JIN Jian, TENG Yiqun
the Jiaxing Second Municipal Hospital
Abstract:
Objective To analyze the characteristics of sleep architecture in children with obstructive sleep apnea/hypopnea syndrome (OSAHS) and those with primary snoring (PS). Methods Ninety six snoring children underwent overnight examination with polysomnography (PSG) to distinguish OSAHS (n=42) and PS(n=54). The parameters of sleep composition were recorded and compared between two groups; and also compared with those with normal group. Results There were no significant differences in measures of sleep architecture, including total sleep time, sleep latency, sleep efficiency, NREM1%, NREM2%, NREM3%, REM%, the micro-arousal index between OSAHS group (n=42) and PS group (n=54) (P >0.05).But the body mass index (BMI) and apnea hypopnea index (AHI) were significantly higher, while the lowest SaO2 was significantly lower in OSAHS group than those of PS group (P<0.05). Compared with the normal children, NREM1% and NREM2% in OSAHS and PS groups were increased, while NREM3% and REM% decreased (all P<0.01). Conclusion Compared to normal children, the sleep architecture in children with OSAHS or PS is changed; however, there are no much differences between two groups.
Key words:  Obstructive sleep apnea hypopnea syndrome Primary snoring Children Sleep architecture Polysomnography