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早期胃印戒细胞癌患者临床病理特征及预后分析
虞哲科, 王晶晶, 邱振明, 张锐利, 杨磊磊, 郑永华, 赵铮铮
台州医院普外科
摘要:
目的探讨早期胃印戒细胞癌患者临床病理特征及预后情况。方法收集经病理学检查确诊的早期胃癌患者286例,分为印戒细胞癌组(55例)和非印戒细胞癌组(231例),回顾性分析并比较两组患者的临床病理特征及预后情况。结果印戒细胞癌组女性患者占50.9%(28/55),≤60岁患者占65.5%(36/55),肿瘤浸润至黏膜层患者占63.6%(35/55),术后5年生存率为90.9%;非印戒细胞癌组女性患者占35.9%(83/231),≤60岁患者占31.2%(72/231),肿瘤浸润至黏膜层患者占47.2%(109/231),术后5年生存率为81.9%。以上指标两组比较,差异均有统计学意义(均P<0.05)。结论早期胃印戒细胞癌常见于年轻女性,肿瘤多浸润至黏膜层,术后短期预后较好。
关键词:  早期胃印戒细胞癌 临床病理特征 生存率 预后
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Clinicopathological characteristics and prognosis of early gastric signet ring cell carcinoma
YU Zheke, WANAG Jingjing, QIU Zhenming, ZHANG Ruili, YANG Leilei, ZHENG Yonghua, ZHAO Zhenzhen
Taizhou Hospital
Abstract:
Objective To examine the clinicopathological characteristics and prognosis of early gastric signet ring cell carcinoma. Methods Clinicopathological data of 286 patients with early gastric cancer admitted in our hospital were retrospectively analyzed, including 55 cases of signet ring cell carcinoma(SRCC) and 231 cases of non signet ring cell carcinoma (NSRCC). Results There were 28 female cases (50.9%), 36 cases aged below 60 years (65.5%) , 35 cases of mucosa infiltration (63.6%), and with a 5-year survival rate of 90.9% in SRCC group, while there were 83 female cases (35.9%), 72 cases aged less than 60 years (31.2%), 109 cases of mucosa infiltration (42.7%), and with a 5-year survival rate of 81.9% in NSRCC group, there were significant differences in above parameters between two groups (P <0.05). Conclusion Early gastric signet ring cell carcinoma is more likely to occur in young age females and to be located in mucosa with a fairly well postoperative prognosis.
Key words:  Early gastric signet ring cell carcinoma linical and pathological characteristics Survival rate Prognosis