| 摘要: |
| 目的不同心血管危险因素暴露对老年人群脑血管血液动力学指标（CVHI）的影响。方法整群抽取不同批次疗休养的老年人620例，60~70岁75例，71~80岁55例，81~90岁442例，91岁以上48例。对入选者进行心血管危险因素调查，检测CVHI并进行积分，分析不同数量危险因素暴露下CVHI及积分的差异。结果（1）71~80岁和81~90岁年龄组CVHI积分在不同心血管危险因素组间比较差异均有统计学意义（均P＜0.01）。（2）81~90岁年龄组的CVHI异常率（CVHI积分＜75）随着心血管危险因素的暴露与聚集呈上升趋势（P＜0.01），同时该组老年人群的Vmean、Vmin的测定值随着心血管危险因素的增多呈下降趋势，脉搏波速度（Pwv）、特性阻抗（Zcv）、外周阻力（RV）、动态阻力（DR）、压差（DP）测定值随着心血管危险因素的增多呈升高趋势（均P＜0.01）。结论60岁以上老年人群的脑血管功能受心血管危险因素的影响，尤其是81~90岁老年人群的CVHI积分变化更为突出。老年人群危险因素暴露和聚集与CVHI变化及其总积分降低密切相关，CVHI可以作为老年人群卒中风险评估和干预的良好指标。 |
| 关键词: 脑血管血液动力学指标 老年人 心血管危险因素 |
| DOI： |
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| Changes of cerebral vascular hemodynamics in relations to cardiovascular disease risk factor exposure in elderly |
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WANG Saiying, LU Meijia, WU Dou
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Hangzhou Wuyunshan Sanatorium
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| Abstract: |
| Objective To investigate the relationship between changes of cerebral vascular hemodynamics indexes (CVHI) and cardiovascular disease risk factor exposure in the elderly. Methods Six hundred and twenty participants aged 60 years were cluster sampled from Hangzhou Wuyunshan Sanatorium, including 75 cases aged 60~70 years, 55 cases aged 71~80 years, 442 cases aged 81~90 years and 48 cases aged 91 years. The risk factors of cardiovascular diseases were investigated and CVHI was evaluated. The CVHI scores were accumulated by a unified approach. The participants were grouped by the number of risk factors of cardiovascular diseases. Finally the differences of CVHI scores in 3 groups were compared respectively. Results The accumulative scores of CVHI and their distributions in 71~80 age group and 81~90 age group had significant differences (P＜0.01). Abnormal rate of CVHI score ( ＜75 points) in participants aged 81~90 years was increasing as risk factor exposure level elevating (P ＜0.01). And Vmean and Vmin in participants aged 81~89 years were decreasing as risk factor exposure level elevating, while Pwv, Zcv, RV,DR and DP were increasing (P＜0.01). Conclusion The CVHI scores in subjects aged 60 years are associated with cardiovascular diseases risk factors, which is more markedly in el- derly aged 81~90 years. CVHI score may be used as ideal indicators for evaluation of stroke risk in elderly. |
| Key words: Cerebral vascular hemodynamics indexes (CVHI) Elderly Risk factors of cardiovascular diseases |
