| 摘要: |
| 目的探讨缺血性脑卒中（CIS）合并糖尿病肾病患者预后的影响因素。方法对527例初发CIS合并糖尿病肾病患者进行研究，以CIS复发或因病死亡为研究终点，分为预后不良组（达到终点事件者）58例和预后良好组（未达到终点事件者）469例，比较两组患者临床特征的差异，采用logistic回归分析法探讨预后的影响因素。结果两组患者年龄、入院改良Rankin评分（mRS）、美国国立卫生研究院卒中评分（NIHSS）、日常生活能力量表（ADL）、糖化血红蛋白、血肌酐、尿蛋白/肌酐比比较，差异均有统计学意义（均P＜0.05）。logistic回归分析显示，入院mRS、NIHSS、ADL、尿蛋白/肌酐比、血肌酐和糖化血红蛋白为CIS合并糖尿病肾病患者预后的影响因素（均P＜0.05）。结论入院mRS、NIHSS、ADL、尿蛋白/肌酐比、血肌酐和糖化血红蛋白为CIS合并糖尿病肾病患者预后的影响因素。 |
| 关键词: 缺血性脑卒中 糖尿病肾病 预后 影响因素 |
| DOI： |
| 分类号: |
| 基金项目:温岭市科技计划基金 |
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| Influencing factors of prognosis in diabetic nephropathy patients with cerebral ischemic stroke |
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ZHANG Li, LIU Xiaoli, JIN Youyu, LI Xiang, ZHANG Xiaoxin
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the First People Hospital of Wenling
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| Abstract: |
| Objective To investigate the influencing factors of prognosis in diabetic nephropathy patients with cerebral ischemic stroke (CIS). Methods A total of 527 patients with CIS and diabetic nephropathy from 4 hospitals in Zhejiang province were included in the study. Endpoint of the study was defined as CIS recurrence or death due to illness. There were 58 patients with poor prognosis (reach the end point) and 469 with good prognosis (not reach the end point). The differences of clinical features were compared between the two groups, and the influencing factors of prognosis were analyzed by logistic regression analysis. Results There were significant differences in the age, Modified Rankin Scale (mRS), National Institute of Health Stroke Scale (NIHSS) and Activity of Daily Living Scale (ADL) scores, glycosylated hemoglobin, serum creatinine, urinary protein/creatinine levels between two groups (P＜0.05). Logistic regression analysis showed that mRS, NIHSS and ADL scores, urinary protein/creatinine, serum creatinine and glycosylated hemoglobin levels were the influencing factors of prognosis in diabetic nephropathy patients with CIS (P＜0.05). Conclusion mRS, NIHSS and ADL scores, urinary protein/creatinine, serum creatinine and glycosylated hemoglobin levels would influence the prognosis in diabetic nephropathy patients with cerebral is- chemic stroke. |
| Key words: Cerebral ischemic stroke Diabetic nephropathy Prognosis Influencing factor |
