| 摘要: |
| 目的比较双镜联合（LECS，即腹腔镜联合胃镜）与开腹手术治疗胃间质瘤（GST）的疗效与安全性。方法检索公开发表的有关LECS（LECS组）与开腹（OPEN组）手术治疗GST的疗效与安全性比较的文献，按纳入标准筛选文献，并进行质量评价后，对提取的临床效应指标进行Meta分析。结果共纳入16篇文献，共1139例患者，其中LECS组578例，OPEN组561例。Meta分析结果显示：与OPEN组比较，LECS组患者术中出血量少（WMD=-62.01，95%CI：-67.91～-56.10，P＜0.05）、术后肛门排气时间早（WMD=-48.76，95%CI：-63.08～-34.43，P＜0.05）、术后进食时间早（WMD=-1.71，95%CI：-2.21～-1.22，P＜0.05）、住院时间短（WMD=-4.28，95%CI：-5.24～-3.33，P＜0.05）、术后并发症发生率低（OR=0.17，95%CI：0.10～0.28，P＜0.05），而手术时间比较差异无统计学意义（P＞0.05）。结论LECS手术治疗GST安全、有效。 |
| 关键词: 胃间质瘤 腹腔镜 胃镜 开腹手术 Meta 分析 |
| DOI：10.12056/j.issn.1006-2785.2017.39.24.2016-1691 |
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| Efficacy and safety of laparoscopic and endoscopic cooperative surgery versus open resection for gastric stromal tumors: a meta-analysis |
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Huzhou Central Hospital
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| Abstract: |
| Objective To evaluate the efficacy and safety of laparoscopic and endoscopic cooperative surgery(LECS) for gastric stromal tumors (GST) by systematic review and meta-analysis. Methods The literature comparing LECS and open resection (OPEN) for GST was searched from several international online databases. After screening for inclusion, quality assessment, and data extraction, meta-analysis was conducted. Results Sixteen studies were included for meta-analysis, involving 1 139 patients with GST, of whom 578 cases with LECS and 561 cases with OPEN for treatment. Compared to OPEN, LECS experienced lower intraoperative blood loss (W MD=-62.01, 95%CI: -67.91--56.10, P＜0.05), shorter time of postoperative flatus(WMD=-48.76, 95%CI: -63.08--34.43, P＜0.05), earlier postoperative feeding(W MD=-1.71, 95%CI:-2.21--1.22, P＜0.05）, shorter length of hospital stay (W MD=-4.28,95% CI:-5.24--3.33, P ＜0.05), and less postoperative complications (OR=0.17, 95% CI: 0.10-0.28, P＜0.05). There was no significant difference in operative time between two groups (P＞0.05). Conclusion Laparoscopic and endoscopic cooperative surgery for resection of gastric stromal tumors is safe and effective. |
| Key words: Gastric stromal tumor Laparoscopy Endoscopy Open surgery Meta-analysis |
