| 摘要: |
| 目的探讨根治性膀胱切除结合淋巴结扩大清扫术治疗浸润性膀胱癌的预后影响因素。方法收集58例行根治性膀胱切除结合淋巴结扩大清扫术治疗的浸润性膀胱癌患者的临床资料，对影响患者的预后因素进行Cox比例风险回归模型分析。结果Cox比例风险回归模型分析结果显示，TNM分期、病理分级、淋巴结是否转移、淋巴结密度是浸润性膀胱癌术后生存的独立影响因素（均P＜0.01）。结论根治性膀胱切除结合淋巴结扩大清扫术治疗浸润性膀胱癌患者的预后较好，TNM分期、病理分级、淋巴结是否转移、淋巴结密度与患者预后有关。 |
| 关键词: 根治性膀胱切除术 淋巴结清扫术 浸润性膀胱癌 预后 影响因素 |
| DOI：10.12056/j.issn.1006-2785.2017.39.12.2016-1840 |
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| Influencing factors related to prognosis of invasive bladder cancer following radical cystectomy with lymph node dissection |
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ZHOU Mi, LIU Feng, WANG Shuai
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Zhejiang provincial People's Hospital
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| Abstract: |
| Objective To explore the influencing factors related to prognosis of invasive bladder cancer following radical cystectomy combined with lymph node dissection. Methods The clinical data of 58 patients with invasive bladder cancer treated by radical cystectomy combined with lymph node dissection in our hospital from January 2004 to September 2011 were retrospectively reviewed. The prognosis of patients after treatment and the factors related to prognosis were analyzed by univariate and multivariate Cox regression model. Results Univariate and multivariate Cox regression analysis showed that TNM stage, pathologic grade, lymph node metastasis and lymph node density were independent prognostic factors for postoperative survival of patients with invasive bladder cancer (all P ＜0.01). Conclusion The prognosis of patients with invasive bladder
cancer after radical cystectomy with lymph node dissection is correlated with TNM stage, pathological grade, lymph node metastasis and lymph node density. |
| Key words: Radical cystectomy surgery Lymph node dissection surgery Invasive bladder Prognosis Influencing
factors |
