| 摘要: | 
			 
		     | 目的探讨杭州地区围绝经期妇女文化程度与其发生围绝经期综合征的关系。方法选取2014年4月至2015年10月在妇科门诊年龄40~60岁的1632例围绝经期妇女,采用问卷方式调查妇女基本健康信息和绝经年龄,采集实验室检查结果,改良Kupperman评分法评估妇女围绝经期症状。结果1501例妇女完成调查研究,杭州地区妇女自然绝经年龄为(49.63±3.43)岁。围绝经期症状发生率前5位依次为潮热多汗(75.56%)、性生活问题(72.61%)、失眠(67.30%)、疲乏(65.56%)、情绪波动(61.90%)。不同文化程度妇女在自然绝经年龄、妊娠次数、分娩次数、BMI、骨密度、感觉异常、抑郁疑心症状、皮肤蚁行感等方面比较,差异均有统计学意义(均P<0.05)。文化程度越低,Kupperman评分总分越高,围绝经期自觉症状越严重(P<0.05)。结论杭州地区妇女自然绝经年龄估计值为49.63岁,绝经年龄和围绝经期相关症状受文化程度影响,对于不同文化程度的围绝经期妇女,临床处理方法应当不同。 | 
			
	         
				| 关键词:  围绝经期  文化程度  围绝经综合征  调查 | 
			 
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                | 基金项目:国家卫生和计划生育委员会科研基金;杭州市医药卫生科技计划重点项目;杭州市科技发展计划项目;杭州市科技局重点项目;浙江省科技厅重大科技专项重点项目 | 
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                | Association of education level of women with their menopausal age and perimenopausal symptoms | 
           
			
                | HUAANG Zheren,WEI Shuangshuang,LIU Wenhua,TANG Shanshan,ZHANG Zhifen | 
           
		   
		   
                | Hangzhou First People's Hospital | 
		   
             
                | Abstract: | 
			
                | Objective To investigate the association of education level of women with their menopausal age and perimenopausal symptoms. Methods  A total of 1632 perimenopausal women  (40~60 years) visiting gynecological clinic  from April 2014 to October 2015 were enrolled in this study. A structured questionnaire was used to collect date of chronic diseases, menopausal age, education level and other information. The menopausal symptoms were evaluated with Kupperman Menopause Index (KMI). Results There were 1 501 women completed the survey with a response rate of 92.0% . The five most frequent symptoms in menopausal women were hot flash(75.56%), sexual problems(72.61%), insomnia(67.30%), fatigue(65.56%),irritability (61.90% ). There were significant differences in natural menopausal age, number of pregnancies, BMI, bone mineral density, paresthesia, prevalence of depression and myrmeciasis among women with different educational levels (all P<0.05), the KMI scores were negatively correlated with the educational levels in perimenopausal women  (P<0.05).   Conclusion   The study sug-
gested that education levels of perimenopausal women are associated with their age of natural menopause and menopausal symptoms. | 
	       
                | Key words:  Menopause   Education   Menopausal syndrome    Investigation |