| 摘要: |
| 目的系统评价尊严疗法对临终患者焦虑、抑郁及希望水平的影响。方法计算机检索PubMed、WebofScience、CochraneLibrary、Scopus、EMBASE、EBSCO、OVID、中国生物医学文献数据库（CBM）、中国知网（CNKI）及万方数据知识服务平台等，收集有关尊严疗法对终末期患者干预效果的原始研究，检索时间均为建库至2017年3月，由2位评价人员按照标准独立筛选文献、提取资料、评价文献质量。采用RevMan5.3分析软件对资料进行统计分析。结果共纳入7个随机对照试验（RCTs），543例患者。Meta分析结果显示，尊严疗法在干预＞1周时能改善临终患者焦虑[SMD=-0.95，95%CI：（-1.86，-0.05），P＜0.01]，抑郁[SMD=-0.85，95%CI：（-1.61，-0.09），P＜0.01],希望水平[SMD=3.74，95%CI：（0.89，6.59），P=0.01]；而干预不足1周时，尊严疗法组和对照组相比，焦虑、抑郁及希望水平改善均无统计学差异(均P＞0.05)。结论尊严疗法干预＞1周时对改善临终患者的焦虑、抑郁及希望水平具有较好的效果，但干预≤1周时效果不明显。受纳入研究数量和质量限制，上述结论尚需要更多高质量研究予以验证。 |
| 关键词: 尊严疗法 临终患者 姑息护理 Meta 分析 |
| DOI：10.12056/j.issn.1006-2785.2018.40.10.2017-1262 |
| 分类号: |
| 基金项目:浙江省医药卫生科技计划项目(2018KY544) |
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| Effect of dignity therapy on depression, anxiety and hope level in terminally ill patients: a systematic review |
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Zhejiang Chinese Medicine University
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| Abstract: |
| Objective To evaluate the effect of dignity therapy (DT) on anxiety, depression and hope level of terminally ill patients. Methods We searched PubMed, Web of Science, Cochrane Library, Scopus, EMBASE, EBSCO, OVID, CBM, CNKI and Wanfang Data from inception to March 2017. The randomized controlled trials (RCTs) studying the effects of DT on depression, anxiety and hope level in terminally ill patients were collected. Literature screening, data extraction, and the bias assessment of all eligible studies were conducted by two reviewers independently. The meta-analysis was conducted using RevMan 5.3 software. Results A total of 7 RCTs involving 543 patients were included. The results of meta-analysis showed that DT significantly improved the anxiety [SMD=-0.95, 95% CI: (-1.86,-0.05), P＜0.01], depression [SMD=-0.85, 95% CI: (-1.61,
-0.09), P＜0.01] and hope level [SMD=3.74, 95%CI: (0.89,6.59), P＜0.05] after one week intervention; however, these effects were not found within one week intervention (P ＞0.05). Conclusion DT is effect ive in improving depression, anxiety and hope level of terminally ill patients after one-week intervention. Due to the limitation of quantity and quality of included studies, more high-quality studies are needed to confirm the above conclusion. |
| Key words: Dignity therapy Terminally ill patients Palliative care Systematic review |
