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子痫前期患者光电容积指脉搏波特征参数变化的研究
封英, 赵柏惠, 陈新忠
浙江大学医学院附属妇产科医院麻醉科
摘要:
目的观察光电容积指脉搏波(PPG)的特征参数下降支面积比(ADR)、脉搏波波幅(PPGA)及脉率间隔(PBI)在子痫前期患者及正常孕妇中的变化,探讨以上参数是否可以预测子痫前期的发生。方法选择孕28~37周的单胎孕妇108例,其中采集脉搏波时无子痫前期,随访整个孕期均正常的孕妇36例(Ⅰ组);采集脉搏波时尚无子痫前期发生,在随访过程中发展为子痫前期36例(Ⅱ组);采集脉搏波时已确诊为子痫前期36例(Ⅲ组)。孕妇休息10min后,坐位,记录左上肢外周血压、心率及身高、体重等一般信息。计算机实时监测记录3组孕妇的ADR、PPGA及PBI。结果Ⅲ组ADR较Ⅰ组及Ⅱ组降低(P<0.05),ADR在Ⅰ组及Ⅱ组间比较差异无统计学意义(P>0.05),3组间PPGA、PBI比较差异均无统计学意义(均P>0.05)。结论ADR在子痫前期患者中明显低于正常孕妇,提示子痫前期患者存在血管阻力与弹性的变化,但PPGA、PBI及ADR不能早期有效的预测子痫前期的发生。
关键词:  光电容积脉搏波 子痫前期 妊娠
DOI:10.12056/j.issn.1006-2785.2017.39.24.2017-2057
分类号:
基金项目:浙江省科技厅科研基金(2014C33171)
Characteristic parameters of photoplethysmography pulse wave in patients with preeclampsia
Women’s Hospital School of Medicine Zhejiang University
Abstract:
Objective To assess the application of potoplethysmographic pulse wave in women with preeclampsia. Methods One hundred and eight women in the third trimester were recruited, including 36 women of normal pregnancy (group 1), 36 women who develop preeclampsia subsequently (group 2) and 36 women with preeclampsia (group 3). The photoplethysmography pulse wave was assessed in three groups. The area difference ratio (ADR), photoplethysmography amplitude(PPGA) and pulse beat interval(PBI) were compared among the three groups. Results Compared with groups 1 and 2, the ADR was decreased in the group 3, (P<0.05), but not PPGA and PBI; while there was no significant difference in ADR between group 1 and group 2. Conclusion ADR is associated with the preeclampsia, but potoplethysmographic pulse wave can not predict the development of preeclampsia.
Key words:  Photoplethysmographic pulse wave Preeclampsia Pregnancy