| 摘要: |
| 目的探讨血清D-二聚体和肠道屏障功能指标在宫颈癌中的临床意义。方法应用紫外线分光光度法检测69例宫颈癌患者血清D-二聚体水平和肠道屏障功能指标（包括D乳酸、细菌内毒素、二胺氧化酶），分析两者与宫颈癌国际妇产科联盟（FIGO）分期的关系。结果不同FIGO分期的宫颈癌患者，其血清D-二聚体、D乳酸水平差异均有统计学意义（均P＜0.05）；细菌内毒素、二胺氧化酶水平差异均无统计学意义（均P＞0.05）。结论宫颈癌患者D-二聚体、D乳酸水平与FIGO分期有关，可指导临床辅助诊断。 |
| 关键词: 宫颈肿瘤 D- 二聚体 肠道屏障 |
| DOI：10.12056/j.issn.1006-2785.2018.40.10.2017-3189 |
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| Clinical significance of serum D-dimer and gut barrier function in cervical cancer |
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Zhejiang Carcer Hospital
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| Abstract: |
| Objective To investigate the clinical significance of serum D-dimer and gut barrier function in malignant cervical tumors. Methods The serum D-dimer and gut barrier function (D-lactic acid, bacterial endotoxin and diamine oxidase) were detected by ultraviolet spectrophotometry in patients with cervical cancer. The relationship of cervical cancer FIGO stage with serum D-dimer and gut barrier function was analyzed. Results The serum D-dimer level was significantly correlated with the FIGO stage of cervical cancer, and serum D-lactate level, squamous cell carcinoma antigen levels in patients (all P＜0.05), and not correlated with the menopause status and the treatment methods of the patients. Conclusion The serum D-dimer and D-lactate levels is correlated with FIGO stage of cervical cancer, which may have clinical diagnostic value. |
| Key words: Cervical cancer D-dimer Gut barrier function |
