| 摘要: |
| 目的分析高脂血症重症急性胰腺炎（HLSAP）的临床特征。方法收集28例HLSAP患者和43例非高脂血症重症急性胰腺炎（NHLSAP）患者的一般资料、TG、TC、LDL-C、TBil、血钙、C反应蛋白（CRP）、红细胞压积、并发症及预后等情况，分析HLSAP出现急性呼吸窘迫综合征（ARDS）的危险因素。结果HLSAP患者好发年龄低，且多伴有糖尿病和脂肪肝，复发率高；HLSAP组的TG、TC、LDL-C、血钙、CRP、红细胞压积等指标与NHLSAP组比较均有统计学差异；HLSAP组ARDS的发生率高于NHLSAP组，且TG是ARDS的独立危险因素。结论HLSAP常合并脂肪肝、糖尿病，且复发率高，早期易出现ARDS表现，因此控制血脂可以降低重症胰腺炎的复发及并发症的出现。 |
| 关键词: 重症急性胰腺炎 高脂血症 临床特征 |
| DOI：10.12056/j.issn.1006-2785.2017.39.22.2017-831 |
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| Clinical characteristics of hyperlipidemic patients with severe acute pancreatitis |
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Taizhou Hospital
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| Abstract: |
| Objective To analyze the clinical characteristics of hyperlipidemic patients with severe acute pancreatitis (HLSAP). Methods Twenty-eight patients with HLSAP were enrolled in this study and 43 non-hyperlipidemic patients with severe acute pancreatitis (NHLSAP) were selected as control group. The general information, laboratory tests (triglycerides, cholesterol, low density lipoprotein, total bilirubin, calcium, C-reactive protein, hematocrit), complications and prognosis were compared between two groups. The risk factors of acute respiratory distress syndrome (ARDS) in HLSAP patients were analyzed. Results The patients with HLSAP were associated with low age, diabetes and fatty liver, the recurrence rate was high in HLSAP group compared with NHLSAP groups. There were significant differences in triglyceride, cholesterol, low density lipoprotein, Calcium, C-reactive protein and hematocrit between two groups. The incidence of ARDS in HLSAP group was higher than that in NHLSAP group, and high triglyceride (TG) level was an independent risk factor for ARDS. Conclusion Hyperlipidemia severe acute pancreatitis is often associated with fatty liver, diabetes, high recurrence rate and early development of ARDS, so control of blood lipids may reduce the recurrence of severe pancreatitis and complications. |
| Key words: Severe acute pancreatitis Hyperlipidemia Clinical features |
