| 摘要: |
| 目的比较3种方法治疗宫颈高危型人乳头瘤病毒（HPV）感染的疗效。方法选择体检确诊为宫颈高危型HPV感染且采用重组干扰素α2a栓+保妇康栓联合治疗（A组）、单用重组干扰素α2a栓治疗（B组）和不用药（C组）各500例为研究对象，6个月后复查HPV并比较3组患者疗效。结果A、B、C组患者治疗后的总有效率分别为84.40%、62.00%和27.00%，即A组＞B组＞C组（P＜0.01）。HPV16（+）、18（+）和其他12（+）型患者治疗后的总有效率分别为58.68%、58.59%和56.68%，差异无统计学意义（P＞0.05）；按照不同治疗效果分层，3组患者痊愈率、有效率和无效率比较，差异均无统计学意义（均P＞0.05）。结论重组干扰素α2a栓+保妇康栓联合治疗宫颈高危型HPV感染的效果明显优于单用重组干扰素α2a栓及不用药，可在临床推广应用。 |
| 关键词: 人乳头瘤病毒 干扰素 保妇康栓 |
| DOI：10.12056/j.issn.1006-2785.2017.39.7.2017-166 |
| 分类号: |
| 基金项目: |
|
| Clinical Observation of Three Therapeutic Schemes for Cervical High-risk HPV Infection |
|
LV Ailan, XU Wen, XU Xia
|
|
Fuyang Masternal and Child Health Care Hospital
|
| Abstract: |
| Objective To study the treatment efficacy of three therapeutic schemes against Human Papillomavirus (HPV)-induced cervical, and to provide scientific evidence for the HPV treatment. Methods 1500 cases of cervical HPV infection were observed in Fuyang District Maternal and Child Health Care Hospital from 2011 to 2014. The cases were divided into three groups, group A treated with recombinant interferon plus Baofukangshuan, group B with recombinant interferon alone, and group C with no medicine used. They were tested for HPV six months later after treatment. The demographic information and
risk factors were collected. SPSS16.0 were used to compare the treatment efficacy among the three groups. Results The total efficiency of group A was 84.40%, higher than groups B 62.00% and group C 27.00%(P＜0.01). Treatment efficiency of HPV 16 (58.68%) was of no statistical difference compared to the HPV 18 (58.59% ) and other types (56.68%) (P＞0.05 ). Conclusion Cervical HPV infection treatment with interferon plus Baofukang is effectively, and it is worthy of application. |
| Key words: Human papillomavirus Interferon Baofukangshuan |
