| 摘要: |
| 褪黑素作为辅助治疗失眠的手段在世界范围内日益增多,然而在正常发育的儿童群体中使用褪黑素的证据和指南建议很少。为填补这一空白、规范褪黑素在正常发育儿童中的应用,2025年国际儿科睡眠协会(IPSA)在评估现有文献的基础上制定了一项专家共识。该共识重点介绍了褪黑素的使用时机、剂量管理以及使用期间安全监测与随访,强调了家长、患者和儿科医生在用药过程中系统评估的重要意义。本文主要对共识进行深入解读,旨在为儿科医生、护理人员及参与儿童睡眠障碍管理的医疗保健从业者提供一份切实可行的规范用药指导。 |
| 关键词: 褪黑素 儿童 国际儿科睡眠协会 专家共识 指南 |
| DOI： |
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| 基金项目:国家自然科学基金面上项目(81973060) |
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| 2025 IPSA Consensus Interpretation: Clinical Application of Melatonin in Typically Developing Children Zheng Ying, Zhao Shi-guo, Fu Cang-cang,et al. Children’s Hospital,Zhejiang University School of Medicine; National Clinical Research Center for Child Health,Hangzhou 310052,China |
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Zhengying, Zhaoshiguo, Fucangcang, Fanxiaoli, Qiufei, Yangrongwang
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Children’s Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health
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| Abstract: |
| The use of melatonin as an adjunctive treatment for insomnia is increasing worldwide, yet there is limited evidence and guideline recommendations for its use in typically developing children. In order to address this gap and standardize melatonin use in this population, the International Pediatric Sleep Association (IPSA) developed an expert consensus in 2025, based on an evaluation of existing literature. The consensus highlights the timing of melatonin use, dosage management, and safety monitoring and follow-up during treatment, emphasizing the importance of systematic assessment involving parents, patients, and pediatricians. This article provides an in-depth interpretation of the consensus, aiming to offer practical guidelines for pediatricians, caregivers, and healthcare professionals involved in managing sleep disorders in children. |
| Key words: Melatonin children International Pediatric Sleep Association expert consensus guidelines |