| 摘要: |
| 目的探讨浙江中北部农村居民代谢综合征（MS）与慢性肾脏病（CKD）的流行病学特征及两者的关系。方法以浙江中北部（磐安县高二乡、海宁市永福村、海宁市许桥村、桐乡市路家园村）4个不同村落、118个村民小组内居住5年以上的18岁以上原住居民为研究对象，通过问卷调查、体格检查及实验室检查进行横断面调查。根据浙江省第6次人口普查数据中乡村地区人口性别、年龄分布计算MS与CKD标化患病率，比较MS患者与未患MS居民基线特征、CKD患病情况。结果在资料完整的1627例居民中共筛查出MS患者218例，患病率为13.40%（95%CI：12.76~16.20）；CKD患者202例，患病率为12.42%（95%CI：8.03~10.85）。MS患者BMI、腰围、收缩压、舒张压、尿酸、空腹血糖、TG、TC均高于未患MS居民（均P＜0.05），HDL-C低于未患MS居民（P＜0.05），而年龄、血肌酐、LDL-C与未患MS居民比较均无统计学差异（均P＞0.05）。MS患者CKD患病率高于未患MS居民（22.02%vs10.93%，P＜0.05）。结论浙江中北部农村居民MS和CKD流行现状并不乐观，MS患者CKD患病率高于未患MS居民，开展CKD早期筛查及相关知识的普及，尽早对MS进行干预非常必要。 |
| 关键词: 代谢综合征 慢性肾脏病 横断面调查 浙江中北部 |
| DOI：10.12056/j.issn.1006-2785.2018.40.9.2017-1907 |
| 分类号: |
| 基金项目:浙江省医药卫生平台计划（重点资助）项目（2015ZDA005） |
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| Prevalence of metabolic syndrome and chronic kidney disease among rural residents in north-central region of Zhejiang province |
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Zhejiang provincial People's Hospital
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| Abstract: |
| Objective To survey the prevalence of metabolic syndrome (MS) and chronic kidney disease(CKD) among rural residents of north-central region of Zhejiang province and to investigate the association between two diseases. Methods A cross-sectional survey on the prevalence of MS and CKD was conducted with questionnaire, physical examination and laboratory examination. Total 1 627 residents aged ≥18 years, who had lived in rural area of north-central Zhejiang (Pan'an,
Haining and Tongxiang) for ≥5 years, were selected as participants. The age-standardized prevalence of MS and CKD was calculated according the 6th population census of Zhejiang province, and the association between the prevalence of CKD and MS was analyzed. Results In 1 627 participants, there were 218 cases of MS with a prevalence rate of 13.40% (95% CI: 12.76~16.20% ) and 202 cases of CKD with a prevalence rate of12.42% (95% CI: 8.03~10.85% ). Compared to non-MS subjects, the BMI, waist circumference, SBP, DBP, UA, FBG, TG, TC in MS residents were higher (All P＜0.05), and HDL-C was lower (P＜0.05), but there were no significant difference in age, serum creatinine, and LDL-C between the two groups (P ＞ 0.05). The prevalence of CKD in MS patients was higher than that in non-MS residents (22.02% vs 10.93%, P ＜0.05). Conclusion The prevalence of CKD with MS among rural residents in north-central Zhejiang is relatively high, and the prevalence rate of CKD in MS patients is higher than that in non-MS inhabitants. So screening of CKD and early intervention of
MS are necessary. |
| Key words: Metabolic syndrome Chronic kidney disease ( CKD) Cross-sectional survey North-central Zhejiang |
